When Peter and Quagmire accidentally switch underwear, they begin to mimic the other’s behavior. Stewie and Doug agree to commit each other’s murders.

An accident leaves Peter with a high-pitched voice, so Jesus coaches him into fending off the choir boys; Stewie is attracted to Lois’ new masculine physique.

Winner of a Snapple contest, Lois uses her winnings to take Meg on a tropical vacation. Flaunting their wealth, the two are kidnapped. Meanwhile, Stewie and Brian undergo “friendship therapy.”